Platelet lifespan is regulated by intrinsic apoptosis.Platelet apoptosis can be triggered by BH3 mimetics that inhibit the pro-survival Bcl-2 family protein, Bcl-xL.Here, we investigated several small molecules that are reported to act as BH3 mimetics and compared their effects to the well-established BH3 mimetic, ABT-737.Platelet phosphatidylserin

In this work, a large 5326058hx deformation, non-linear semi-analytical model for an all-elastomer, capacitive tactile unit-sensor is developed.The model is capable of predicting the response of such sensors over their entire sensing range under the application of normal forces.In doing so the finite flat punch indentation model developed earlier i

Work integrated learning (WIL), particularly placement-based WIL (P-WIL), has gained momentum in Higher Education over the last decade as an educational strategy for enhancing student employability.However, there is very limited guidance on effective ways to embed and scaffold WIL assessments across courses (degree programs).We present the findings

Chronic constipation is a disorder frequently encountered in clinical practice.Here, we describe the use of ultrasonography as a new approach to the follow-up of adult patients with functional chronic constipation.Specifically, we report two cases of functional chronic constipation: fecal retention in the rectum and not fecal retention in the rectu

IPhone as one of the smartphone brand, is often regarded as a prestigious symbol for teenagers.In choosing goods, teenagers also pay attention to the symbolic value that they want to show.These symbols give here a certain impact to their self-esteem among teenager.What about the non-iPhone user? The purpose of this study was to see the difference o